SCHEMBL28611348

SCHEMBL28611348

COc1cc(CC(=O)O)c(CC(=O)O)cc1CC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.62
CYP3A4 P08684 1/20 0.60
GAA P10253 3/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
KDM4E B2RXH2 2/20 0.45
POLB P06746 2/20 0.45
ABL1 P00519 1/20 0.45
MAPT P10636 1/20 0.45
RECQL P46063 1/20 0.45
RIN1 Q13671 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
SELP P16109 1/20 0.44
NR1H4 Q96RI1 1/20 0.44
CA5A P35218 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
HMGCR P04035 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11420544 0.96 HSD17B10 (0.67) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL27917034 0.92 CYP3A4 (0.71) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL16109698 0.91 HSD17B10 (0.61) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL15760015 0.86 HSD17B10 (0.57) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL11328148 0.86 HSD17B10 (0.57) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL14123786 0.85 HSD17B10 (0.56) HSD17B10CYP3A4GAANPSR1TAAR1
SCHEMBL16527104 0.84 HSD17B10 (0.59) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL2305820 0.82 HSD17B10 (0.57) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL3326963 0.81 HSD17B10 (0.56) HSD17B10CYP3A4GAANPSR1ALDH1A1
SCHEMBL1145675 0.81 HSD17B10 (0.51) HSD17B10CYP3A4GAANPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166079-A Redox active compounds and their use 克姆布鲁项目公司 2021-07-23 CN disclosed