Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.85 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.65 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.65 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16659460 | 0.92 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL28614305 | 0.86 | FGFR2 (0.78) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL22172205 | 0.84 | FGFR1 (0.86) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL16659549 | 0.84 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL28920606 | 0.84 | FGFR1 (0.87) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL28623393 | 0.84 | FGFR1 (0.66) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL28619938 | 0.84 | FGFR1 (0.81) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL28624448 | 0.83 | FGFR1 (0.83) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL28617972 | 0.83 | FGFR1 (0.83) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL28605669 | 0.83 | FGFR1 (0.81) | FGFR1FGFR2FGFR3FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400092-B | Pyrimidine derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2021-08-24 | — | — | CN | disclosed |