Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24189702 | 0.78 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HPGDGPR119 | |
| SCHEMBL1409610 | 0.78 | CHRM2 (0.44) | CHRM2CHRM1CHRM3HPGDDDB1 | |
| SCHEMBL6073716 | 0.77 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDGPR119 | |
| SCHEMBL15114582 | 0.70 | CHRM2 (0.42) | CHRM2CHRM1CHRM3HPGDGPR119 | |
| SCHEMBL5373290 | 0.69 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDGPR119 | |
| SCHEMBL3833624 | 0.69 | — | — | |
| SCHEMBL5152932 | 0.69 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDGPR119 | |
| SCHEMBL7518562 | 0.69 | HSD17B10 (0.32) | HPGDHSD17B10USP2SMN1; SMN2 | |
| SCHEMBL1574379 | 0.67 | CHRM2 (0.40) | CHRM2CHRM1CHRM3HPGDGPR119 | |
| SCHEMBL26923453 | 0.67 | CHRM2 (0.40) | CHRM2CHRM1CHRM3HPGDGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928124-B | Preparation method of saxagliptin intermediate | 上海现代制药股份有限公司 | 2021-07-30 | — | — | CN | disclosed |