SCHEMBL2861213

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2860421	0.84	MAPK10 (0.56)	MAPK10MAPKAPK2ITKTTKAURKA
	SCHEMBL13207534	0.79	TTK (0.47)	ITKTTKPLK4AURKACHEK2
	SCHEMBL2868617	0.78	MAPK10 (0.58)	MAPK10MAPKAPK2ITKTTKTNIK
	SCHEMBL2861747	0.78	MAPK10 (0.78)	MAPK10MAPKAPK2ITK
	SCHEMBL2862258	0.77	MAPK10 (0.64)	MAPK10MAPKAPK2ITKAURKAAURKB
	SCHEMBL2862255	0.77	MAPK10 (0.64)	MAPK10MAPKAPK2ITKAURKAAURKB
	SCHEMBL2862761	0.76	MAPK10 (0.76)	MAPK10MAPKAPK2ITK
	SCHEMBL2862759	0.76	MAPK10 (0.76)	MAPK10MAPKAPK2ITK
	SCHEMBL5380014	0.75	MAPK10 (0.56)	MAPK10MAPKAPK2ITKTTKJAK2
	SCHEMBL5377524	0.74	MAPK10 (0.53)	MAPK10MAPKAPK2ITKTNIKJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.