Altretamine

Altretamine

SCHEMBL28612919

CN(C)c1nc(N(C)C)nc(N(C)C)n1.OCNc1nc(NCO)nc(NCO)n1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
LMNA P02545 2/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
CREBBP Q92793 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH1A1 P00352 4/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.45
GAA P10253 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.41
CYP2C19 P33261 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
HTT P42858 1/20 0.40
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11041803 0.86 GAA (0.43) CYP1A2LMNATHRBBLMCREBBP
Formaldehyde SCHEMBL1979611 0.82 GAA (0.43) CYP1A2LMNATHRBBLMCREBBP
SCHEMBL13042473 0.80 GAA (0.44) CYP1A2LMNAALDH1A1SMN1; SMN2KDM4E
Hexamethylolmelamine SCHEMBL62548 0.80 KMT2A (0.39) CYP1A2LMNAALDH1A1KDM4EGAA
SCHEMBL11764172 0.78 GAA (0.42) CYP1A2LMNAALDH1A1KDM4EPOLB
SCHEMBL6274301 0.78 GAA (0.38) CYP1A2ALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL1817685 0.78 GAA (0.50) CYP1A2LMNATHRBBLMCREBBP
SCHEMBL1817811 0.78 GAA (0.50) CYP1A2LMNATHRBBLMCREBBP
Hexamethylolmelamine SCHEMBL11651779 0.77 KMT2A (0.39) CYP1A2LMNAALDH1A1GAAL3MBTL1
Hexamethylolmelamine SCHEMBL8590629 0.75 KMT2A (0.39) CYP1A2LMNAALDH1A1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110359044-B Preparation method of steel matrix surface super-hydrophobic film 重庆大学 2021-08-24 CN disclosed