Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 19/20 | 0.68 |
| ▸ | EP300 | Q09472 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617513 | 0.86 | KDM4E (0.68) | CREBBPEP300KDM4EALDH1A1POLB | |
| SCHEMBL28612575 | 0.83 | CREBBP (0.69) | CREBBPEP300 | |
| SCHEMBL28616581 | 0.81 | CREBBP (0.62) | CREBBPEP300 | |
| SCHEMBL28613811 | 0.81 | CREBBP (0.69) | CREBBPEP300 | |
| SCHEMBL28616241 | 0.80 | CREBBP (0.70) | CREBBPEP300 | |
| SCHEMBL28623973 | 0.80 | CREBBP (0.65) | CREBBPEP300 | |
| SCHEMBL28614746 | 0.79 | CREBBP (0.70) | CREBBPEP300 | |
| SCHEMBL28612582 | 0.79 | CREBBP (0.71) | CREBBPEP300 | |
| SCHEMBL28612022 | 0.77 | CREBBP (0.67) | CREBBPEP300 | |
| SCHEMBL2815016 | 0.77 | KDM4E (0.64) | CREBBPEP300KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321640-A | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2021-08-31 | — | — | CN | disclosed |