SCHEMBL28613772

SCHEMBL28613772

CN(C(=O)OC(C)(C)C)C1(O)CCNCC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29112686 0.90
SCHEMBL28024842 0.87 ASGR1 (0.33)
SCHEMBL6119041 0.84 KDM4E (0.31) KDM4EKMT2A
SCHEMBL9264114 0.79 KDM4E (0.38) KDM4EKMT2A
SCHEMBL1770679 0.77
SCHEMBL3294635 0.77
SCHEMBL17624334 0.76 HDAC6 (0.33)
SCHEMBL25075599 0.74 HDAC6 (0.33)
SCHEMBL1313232 0.74 KDM4E (0.35) KDM4EKMT2A
SCHEMBL14829034 0.73 ASGR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848577-B N- (hetero) aryl-substituted heterocyclic derivatives useful in the treatment of diseases or conditions associated with the central nervous system 克罗诺斯治疗有限公司 2023-09-01 CN disclosed
CN-109475531-B Heterocyclic inhibitors of PTPN11 得克萨斯州立大学董事会 2021-08-17 CN disclosed