Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HK1 | P19367 | 1/20 | 0.59 |
| ▸ | GALK1 | P51570 | 1/20 | 0.59 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isatin SCHEMBL31087266 | 1.00 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL21316073 | 0.76 | MEN1 (0.63) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL28894653 | 0.74 | MAPT (0.61) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL29594088 | 0.74 | MAPT (0.61) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL28363963 | 0.73 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL30608708 | 0.73 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL17460456 | 0.73 | MEN1 (0.42) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL8690288 | 0.73 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL692422 | 0.73 | IDO1 (0.53) | MEN1KMT2AMAPTALDH1A1APAF1 | |
| SCHEMBL28604179 | 0.73 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396203-B | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2025-03-25 | — | — | CN | claimed |
| CN-116396203-A | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2023-07-07 | — | — | CN | claimed |
| CN-113278007-B | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2022-05-17 | — | — | CN | claimed |
| CN-113278007-A | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2021-08-20 | — | — | CN | claimed |
| CN-116396203-B | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116396203-B | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116396203-A | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-116396203-A | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-116396203-A | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-113278007-B | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113278007-A | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2021-08-20 | — | — | CN | disclosed |