Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 9/20 | 0.49 |
| ▸ | FLT4 | P35916 | 4/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NUAK1 | O60285 | 4/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249034 | 0.91 | JAK3 (0.46) | DDR2FLT4JAK1JAK3KDR | |
| SCHEMBL24853534 | 0.91 | JAK3 (0.46) | DDR2FLT4JAK1JAK3KDR | |
| SCHEMBL28605842 | 0.90 | DDR2 (0.47) | DDR2FLT4JAK1JAK3KDR | |
| SCHEMBL28919423 | 0.88 | DDR2 (0.46) | DDR2FLT4JAK1JAK3KDR | |
| SCHEMBL28612297 | 0.86 | DDR2 (0.49) | DDR2JAK1JAK3IGF1R | |
| SCHEMBL22090272 | 0.86 | DDR2 (0.49) | DDR2JAK1JAK3IGF1R | |
| SCHEMBL29942255 | 0.86 | DDR2 (0.49) | DDR2JAK1JAK3IGF1R | |
| SCHEMBL22089923 | 0.84 | JAK3 (0.48) | DDR2FLT4JAK1JAK3KDR | |
| SCHEMBL28919837 | 0.84 | JAK3 (0.48) | DDR2FLT4JAK1JAK3KDR | |
| SCHEMBL29941940 | 0.84 | JAK3 (0.48) | DDR2FLT4JAK1JAK3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227074-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods | 凌科药业(杭州)有限公司 | 2021-08-06 | — | — | CN | disclosed |