Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28439716 | 1.00 | NPSR1 (0.47) | NPSR1ALDH1A1GAAMAPTALPG | |
| Bromide SCHEMBL28618528 | 1.00 | NPSR1 (0.47) | NPSR1ALDH1A1GAAMAPTALPG | |
| Bromide SCHEMBL29021907 | 1.00 | NPSR1 (0.47) | NPSR1ALDH1A1GAAMAPTALPG | |
| Bromide SCHEMBL28380380 | 1.00 | NPSR1 (0.47) | NPSR1ALDH1A1GAAMAPTALPG | |
| Bromide SCHEMBL28602408 | 1.00 | NPSR1 (0.47) | NPSR1ALDH1A1GAAMAPTALPG | |
| Bromide SCHEMBL28492942 | 1.00 | NPSR1 (0.47) | NPSR1ALDH1A1GAAMAPTALPG | |
| Bromide SCHEMBL28822033 | 0.98 | NPSR1 (0.43) | NPSR1ALDH1A1GAAMAPTALPG | |
| SCHEMBL27647054 | 0.98 | NPSR1 (0.48) | NPSR1ALDH1A1GAAMAPTALPG | |
| SCHEMBL27658952 | 0.98 | NPSR1 (0.48) | NPSR1ALDH1A1GAAMAPTALPG | |
| SCHEMBL28190376 | 0.98 | NPSR1 (0.48) | NPSR1ALDH1A1GAAMAPTALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113233562-A | Antibacterial flocculant containing quaternary phosphonium salt modified locust bean gum | 广州市尚信净化工程有限公司 | 2021-08-10 | — | — | CN | disclosed |