Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | PRKCA | P17252 | 5/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605824 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL28614977 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL28617361 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL28609770 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL28602883 | 1.00 | MAPT (0.80) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL28612066 | 0.93 | MAPT (0.68) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL380745 | 0.89 | MAPT (1.00) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL723509 | 0.89 | MAPT (1.00) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL2934617 | 0.89 | MAPT (1.00) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL2508639 | 0.89 | MAPT (1.00) | MAPTMAPK1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113260607-A | Modified amine lipids | 英特利亚治疗股份有限公司 | 2021-08-13 | — | — | CN | disclosed |