Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26657519 | 0.82 | GRIN2D (0.48) | EPHX2CA12GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5090033 | 0.73 | EPHX2 (0.47) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5101830 | 0.72 | EPHX2 (0.42) | EPHX2CA12GRIN2DGRIN3BGRIN1 | |
| Fluoride SCHEMBL4453455 | 0.72 | EPHX2 (0.46) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1046838 | 0.72 | EPHX2 (0.46) | EPHX2CA12TSHRCA9NPSR1 | |
| SCHEMBL23185440 | 0.70 | EPHX2 (0.41) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26849803 | 0.70 | MEN1 (0.41) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12256144 | 0.69 | EPHX2 (0.40) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3110039 | 0.69 | EPHX2 (0.47) | EPHX2TSHRNPSR1ALDH1A1 | |
| Ethylene SCHEMBL1043237 | 0.69 | EPHX2 (0.43) | EPHX2CA12TSHRNPSR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556244-B | Fused ring compound, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2021-09-03 | — | — | CN | disclosed |