Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183883 | 0.81 | HPGD (0.59) | HPGDSMN1; SMN2L3MBTL1MAPK1ACACB | |
| SCHEMBL20183911 | 0.78 | HPGD (0.50) | HPGDSMN1; SMN2L3MBTL1MAPK1ACACB | |
| SCHEMBL3644126 | 0.76 | GRM5 (0.71) | HPGDSMN1; SMN2L3MBTL1MAPK1ACACB | |
| SCHEMBL3644132 | 0.74 | EPHX2 (0.66) | HPGDSMN1; SMN2L3MBTL1MAPK1ACACB | |
| SCHEMBL21360559 | 0.74 | HPGD (0.60) | HPGDSMN1; SMN2L3MBTL1MAPK1ACACB | |
| SCHEMBL10720943 | 0.74 | PHGDH (0.81) | HPGDSMN1; SMN2L3MBTL1MAPK1PHGDH | |
| SCHEMBL7338701 | 0.73 | PHGDH (0.65) | HPGDSMN1; SMN2L3MBTL1MAPK1PHGDH | |
| SCHEMBL5048054 | 0.73 | HPGD (0.59) | HPGDSMN1; SMN2L3MBTL1MAPK1ACACB | |
| SCHEMBL15904115 | 0.72 | PHGDH (0.63) | HPGDSMN1; SMN2L3MBTL1MAPK1PHGDH | |
| SCHEMBL21524887 | 0.72 | PHGDH (0.63) | HPGDSMN1; SMN2L3MBTL1MAPK1PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349874-B | Compound having BLT inhibitory activity and composition for preventing or treating inflammatory disease comprising the same as active ingredient | 东国大学校产学协力团 | 2021-07-27 | — | — | CN | disclosed |