Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624131 | 0.95 | TSHR (0.55) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL12502274 | 0.88 | TSHR (0.49) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL29950690 | 0.85 | CA12 (0.47) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL763540 | 0.85 | CA12 (0.47) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL17912412 | 0.81 | TSHR (0.58) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL13663882 | 0.81 | TSHR (0.57) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL30622008 | 0.80 | ATM (0.56) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL9850701 | 0.80 | TSHR (0.55) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL8490256 | 0.80 | TSHR (0.59) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL19762346 | 0.78 | TSHR (0.53) | TSHRTDP1L3MBTL1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113133969-B | Glucose-responsive insulin multivesicular liposome and preparation method and application thereof | 中国药科大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113133969-A | Glucose-responsive insulin multivesicular liposome and preparation method and application thereof | 中国药科大学 | 2021-07-20 | — | — | CN | disclosed |