Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810857 | 1.00 | PDE4B (0.41) | PDE4BACACBBTKHRH3PDE3B | |
| SCHEMBL20069362 | 0.81 | CHRM4 (0.48) | ACACBPDE3BPDE3APDE10ACHRM2 | |
| SCHEMBL21810906 | 0.79 | KDM5A (0.47) | ACACBBTKHRH3PDE3BPDE3A | |
| SCHEMBL20137809 | 0.78 | BTK (0.47) | ACACBBTKHRH3 | |
| SCHEMBL20137808 | 0.78 | BTK (0.47) | ACACBBTKHRH3 | |
| SCHEMBL20147442 | 0.77 | ACACB (0.39) | ACACBHRH3PDE3BPDE3APDE10A | |
| SCHEMBL20152054 | 0.77 | HRH3 (0.48) | ACACBHRH3PDE3BPDE3APDE10A | |
| SCHEMBL2244980 | 0.76 | SMN1; SMN2 (0.48) | SLC6A2SLC6A4CHRM2CHRM3 | |
| SCHEMBL27965500 | 0.76 | SMN1; SMN2 (0.51) | PDE4BACACBHRH3CHRM2 | |
| SCHEMBL5266382 | 0.75 | HRH3 (0.46) | ACACBBTKHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302183-A | Cyclic ureas | 圣瑞诺有限公司 | 2021-08-24 | — | — | CN | disclosed |