Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 8/20 | 0.38 |
| ▸ | GABRD | O14764 | 8/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660074 | 0.90 | HPGD (0.43) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL30466734 | 0.90 | HPGD (0.43) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL22090566 | 0.90 | HPGD (0.43) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL21822693 | 0.90 | HPGD (0.43) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL22090784 | 0.89 | HPGD (0.42) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL28582249 | 0.88 | HPGD (0.41) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL30169634 | 0.87 | HPGD (0.40) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL21822605 | 0.87 | HPGD (0.40) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL21822842 | 0.87 | FFAR4 (0.40) | HPGDALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL30169725 | 0.87 | FFAR4 (0.40) | HPGDALDH1A1CYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113286792-B | N-chromen-4-one containing derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-113286792-A | N-containing chromen-4-one derivatives for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-20 | — | — | CN | disclosed |