Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21953399 | 1.00 | AKR1C4 (0.71) | AKR1C4AKR1C3AKR1C2HTTCYP2D6 | |
| SCHEMBL11751129 | 1.00 | AKR1C4 (0.71) | AKR1C4AKR1C3AKR1C2HTTCYP2D6 | |
| SCHEMBL29785187 | 1.00 | AKR1C4 (0.71) | AKR1C4AKR1C3AKR1C2HTTCYP2D6 | |
| SCHEMBL11751123 | 1.00 | AKR1C4 (0.71) | AKR1C4AKR1C3AKR1C2HTTCYP2D6 | |
| SCHEMBL11988493 | 0.92 | AKR1C4 (0.71) | AKR1C4AKR1C3AKR1C2HTTPTGER2 | |
| SCHEMBL12742419 | 0.90 | AKR1C4 (0.67) | AKR1C4AKR1C3AKR1C2HTTPTGER2 | |
| SCHEMBL10022807 | 0.88 | AKR1C4 (0.66) | AKR1C4AKR1C3AKR1C2HTTPTGER2 | |
| SCHEMBL10022805 | 0.88 | AKR1C4 (0.66) | AKR1C4AKR1C3AKR1C2HTTPTGER2 | |
| SCHEMBL13063220 | 0.88 | AKR1C4 (0.66) | AKR1C4AKR1C3AKR1C2HTTPTGER2 | |
| Methyl Jasmonate SCHEMBL23196389 | 0.88 | AKR1C4 (0.72) | AKR1C4AKR1C3AKR1C2HTTPTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50250-E1 | Process for the preparation of cis-alpha,beta substituted cyclopentanones | FIRMENICH SA (CH) | 2024-12-31 | — | — | US | disclosed |
| US-11339113-B2 | Process for the preparation of cis-alpha,beta substituted cyclopentanones | FIRMENICH SA (CH) | 2022-05-24 | — | — | US | disclosed |
| CN-112638861-A | Process for preparing cis-alpha, beta-substituted cyclopentanones | 弗门尼舍有限公司 | 2021-04-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339113-B2 | Process for the preparation of cis-alpha,beta substituted cyclopentanones | CYP4A11, CYP11B1, CYP51A1 | AKR1C4 19/4885AKR1C3 16/4885AKR1C2 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.