1,2-Dimethoxybenzene

1,2-Dimethoxybenzene

SCHEMBL28616635

COc1ccccc1OC.N#CC#N

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.72
CA2 P00918 3/20 0.72
CA7 P43166 2/20 0.72
CA9 Q16790 2/20 0.72
CA12 O43570 1/20 0.72
CA4 P22748 1/20 0.72
CA14 Q9ULX7 1/20 0.72
TP53 P04637 2/20 0.56
TSHR P16473 1/20 0.56
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 2/20 0.54
HTT P42858 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ENPP2 Q13822 1/20 0.52
ORAI1 Q96D31 1/20 0.50
ORAI2 Q96SN7 1/20 0.50
ORAI3 Q9BRQ5 1/20 0.50
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dimethoxybenzene SCHEMBL27631281 0.92 CA1 (0.68) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL27532746 0.89 CA1 (0.72) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL27891985 0.85 CA1 (0.87) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL7895992 0.85 CA1 (0.87) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL29351917 0.85 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL105872 0.85 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL5308636 0.85 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL8501748 0.82 CA1 (0.81) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL11638262 0.82 CA1 (0.81) CA1CA2CA7CA9CA12
SCHEMBL2405150 0.82 CA1 (0.62) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113322057-A Adsorption inhibitor, preparation method and application thereof 中国石油化工股份有限公司 2021-08-31 CN claimed