Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28616706 | 1.00 | GSR (0.62) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL28623413 | 0.98 | GSR (0.65) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL28960644 | 0.98 | GSR (0.65) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL3907029 | 0.98 | GSR (0.65) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL28623414 | 0.98 | GSR (0.65) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL28922053 | 0.97 | GSR (0.62) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL28922054 | 0.97 | GSR (0.62) | GSRPOLBTDP1CYP3A4PARP1 | |
| Phthalic Acid SCHEMBL28621043 | 0.91 | GSR (0.56) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL28961119 | 0.90 | GSR (0.54) | GSRPOLBTDP1CYP3A4PARP1 | |
| Lysine SCHEMBL2226154 | 0.89 | GSR (0.61) | GSRPOLBTDP1PARP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150267-A | Amino acid-based polymer with antiviral and antibacterial functions and preparation method thereof | 中鼎凯瑞科技成都有限公司 | 2021-07-23 | — | — | CN | disclosed |