Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.50 |
| ▸ | PIP4K2A | P48426 | 5/20 | 0.43 |
| ▸ | PIP4K2B | P78356 | 5/20 | 0.43 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | BCR | P11274 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375500 | 0.94 | ABL1 (0.47) | PIP4K2CABL1BCRMAPTKDM4E | |
| SCHEMBL28621552 | 0.94 | PIP4K2C (0.46) | PIP4K2CPIP4K2APIP4K2BPIKFYVEAURKA | |
| SCHEMBL1242034 | 0.93 | PIP4K2C (0.49) | PIP4K2CPIP4K2APIP4K2BPIKFYVEAURKA | |
| Benzamide SCHEMBL28526510 | 0.93 | PIP4K2C (0.46) | PIP4K2CPIP4K2APIP4K2BPIKFYVEAURKA | |
| SCHEMBL1243893 | 0.93 | PIP4K2C (0.51) | PIP4K2CPIP4K2APIP4K2BPIKFYVEAURKA | |
| SCHEMBL1244440 | 0.91 | PIP4K2C (0.49) | PIP4K2CPIP4K2APIP4K2BPIKFYVEMAPT | |
| SCHEMBL1244422 | 0.90 | KDM4E (0.54) | PIP4K2CPIP4K2APIP4K2BPIKFYVEMAPT | |
| SCHEMBL1243665 | 0.90 | PIP4K2C (0.49) | PIP4K2CPIP4K2APIP4K2BPIKFYVEABL1 | |
| SCHEMBL1244613 | 0.89 | PIP4K2C (0.51) | PIP4K2CPIP4K2APIP4K2BPIKFYVEMAPT | |
| SCHEMBL1244323 | 0.89 | PIP4K2C (0.47) | PIP4K2CPIP4K2APIP4K2BPIKFYVEAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365610-A | Methods of making and delivering bisantrene formulations | 现代化制药公司 | 2021-09-07 | — | — | CN | disclosed |