Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | XBP1 | P17861 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MPI | P34949 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616945 | 1.00 | MAPT (0.67) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31686243 | 0.91 | MEN1 (0.58) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17899535 | 0.87 | LY96 (0.72) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL22822886 | 0.85 | KMT2A (0.69) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL22550785 | 0.83 | MAPT (0.67) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL22550921 | 0.83 | MAPT (0.70) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL22462345 | 0.83 | MAPT (0.70) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28618884 | 0.81 | CYP2C9 (0.64) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28618885 | 0.81 | CYP2C9 (0.64) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6855774 | 0.81 | MAPT (1.00) | MAPTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354577-B | Monocarbonyl curcuminoid compound and preparation method and application thereof | 西南医科大学附属中医医院 | 2022-08-26 | — | — | CN | disclosed |
| CN-113354577-A | Monocarbonyl curcumin analogue and preparation and application thereof | 西南医科大学附属中医医院 | 2021-09-07 | — | — | CN | disclosed |