Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605415 | 0.96 | HDAC6 (0.59) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28919764 | 0.93 | HDAC6 (0.55) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28617748 | 0.91 | HDAC6 (0.59) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28605639 | 0.89 | HDAC6 (0.54) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28609779 | 0.89 | HDAC6 (0.55) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28618140 | 0.88 | HDAC6 (0.61) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28614892 | 0.87 | HDAC6 (0.62) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28605597 | 0.85 | HDAC6 (0.56) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28606556 | 0.84 | HDAC6 (0.59) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28607527 | 0.84 | HDAC6 (0.57) | HDAC6HDAC1HDAC10HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-B | Tricyclic compounds and uses thereof | 上海辉启生物医药科技有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |