Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618153 | 0.95 | HDAC6 (0.51) | HDAC6NAMPTPTGDR2HDAC1HDAC10 | |
| SCHEMBL28605597 | 0.94 | HDAC6 (0.56) | HDAC6NAMPTPTGDR2HDAC1HDAC10 | |
| SCHEMBL28609779 | 0.93 | HDAC6 (0.55) | HDAC6NAMPTPTGDR2HDAC1HDAC10 | |
| SCHEMBL28607527 | 0.91 | HDAC6 (0.57) | HDAC6NAMPTPTGDR2HDAC1HDAC10 | |
| SCHEMBL28919764 | 0.89 | HDAC6 (0.55) | HDAC6NAMPTPTGDR2HDAC1HDAC10 | |
| SCHEMBL28605819 | 0.86 | HDAC6 (0.55) | HDAC6NAMPTPTGDR2HDAC1HDAC10 | |
| SCHEMBL28605639 | 0.85 | HDAC6 (0.54) | HDAC6NAMPTPTGDR2HDAC1HDAC10 | |
| SCHEMBL28618140 | 0.85 | HDAC6 (0.61) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28605415 | 0.83 | HDAC6 (0.59) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28617748 | 0.83 | HDAC6 (0.59) | HDAC6PTGDR2HDAC1HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |