SCHEMBL2861793

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2866807	0.90	DYRK1A (0.52)	DYRK1AMAP4K4MAP2K4GSK3AGSK3B
	SCHEMBL2868590	0.87	DYRK1A (0.50)	DYRK1AMAP4K4MAP2K4GSK3AGSK3B
	SCHEMBL2867207	0.85	KDR (0.48)	DYRK1AGSK3BWNT1MAP3K5MAPK8
	SCHEMBL2862730	0.83	DYRK1A (0.59)	DYRK1AMAP3K5
	SCHEMBL2866826	0.82	DYRK1A (0.52)	DYRK1AMAP4K4MAP2K4GSK3AGSK3B
	SCHEMBL2857674	0.81	MAP2K4 (0.60)	MAP2K4GSK3AGSK3BMAP2K7
	SCHEMBL4334482	0.81	MAP4K4 (0.51)	DYRK1AMAP4K4MAP2K4GSK3AGSK3B
	SCHEMBL4149348	0.81	CHEK1 (0.48)	DYRK1AMAP4K4WNT1RIPK1KDR
	SCHEMBL4149353	0.81	CHEK1 (0.48)	DYRK1AMAP4K4WNT1RIPK1KDR
	SCHEMBL2865663	0.80	DYRK1A (0.48)	DYRK1AMAP4K4MAP2K4GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.