Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.62 |
| ▸ | TNF | P01375 | 1/20 | 0.62 |
| ▸ | IL1B | P01584 | 1/20 | 0.62 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612725 | 0.99 | CRBN (0.61) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL26320556 | 0.96 | CRBN (0.63) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL26324033 | 0.96 | CRBN (0.62) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL26320535 | 0.96 | CRBN (0.62) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL26320519 | 0.96 | CRBN (0.62) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL26320573 | 0.96 | CRBN (0.62) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL328600 | 0.93 | CRBN (0.59) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL283111 | 0.92 | CRBN (0.58) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL17049841 | 0.88 | CRBN (0.59) | CRBNDDB1TNFIL1BIKZF3 | |
| SCHEMBL30618973 | 0.88 | DDB1 (0.67) | CRBNDDB1TNFIL1BIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512589-A | Dimeric immunomodulatory compounds against CEREBLON-based mechanisms | H·李·莫菲特癌症中心研究有限公司 | 2021-03-16 | — | — | CN | disclosed |