Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.80 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.80 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.80 |
| ▸ | RET | P07949 | 3/20 | 0.80 |
| ▸ | SRC | P12931 | 3/20 | 0.80 |
| ▸ | PLK4 | O00444 | 2/20 | 0.80 |
| ▸ | AURKA | O14965 | 2/20 | 0.80 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.80 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.80 |
| ▸ | ABL1 | P00519 | 2/20 | 0.80 |
| ▸ | LCK | P06239 | 2/20 | 0.80 |
| ▸ | FYN | P06241 | 2/20 | 0.80 |
| ▸ | LYN | P07948 | 2/20 | 0.80 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.80 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.80 |
| ▸ | AXL | P30530 | 2/20 | 0.80 |
| ▸ | FRK | P42685 | 2/20 | 0.80 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.80 |
| ▸ | BLK | P51451 | 2/20 | 0.80 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606251 | 0.92 | KDR (0.76) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL16628085 | 0.90 | KDR (1.00) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL28919879 | 0.85 | KDR (0.69) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL13059754 | 0.84 | KDR (0.73) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL14422929 | 0.84 | KDR (0.85) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL21125212 | 0.84 | KDR (0.85) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL28612395 | 0.84 | KDR (0.67) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL13648235 | 0.83 | KDR (0.78) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL16628087 | 0.83 | KDR (0.83) | KDRMAPK14TNNI3KRETSRC | |
| SCHEMBL21124526 | 0.82 | KDR (0.85) | KDRMAPK14TNNI3KRETSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264874-A | Substituted diaryl urea derivative and preparation method and application thereof | 华东理工大学 | 2021-08-17 | — | — | CN | disclosed |