Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 19/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864692 | 0.93 | KCNA3 (0.57) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2877542 | 0.93 | KCNA3 (0.54) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2878433 | 0.93 | KCNA3 (0.54) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2864768 | 0.91 | KCNA3 (0.60) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2857522 | 0.91 | KCNA3 (0.60) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2855035 | 0.91 | KCNA3 (0.62) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL6222344 | 0.91 | KCNA3 (0.62) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2858571 | 0.90 | KCNA3 (0.51) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2855127 | 0.90 | KCNA3 (0.51) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2861845 | 0.89 | KCNA3 (0.56) | KCNA3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253328-A1 | Cycloalkyl inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2010-11-24 | — | — | EP | disclosed |