Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464235 | 0.86 | MAPT (0.41) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL24455511 | 0.77 | MAPT (0.42) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL29273417 | 0.74 | NOTUM (0.36) | LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL20722879 | 0.72 | KMT2A (0.37) | MAPTALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL23355481 | 0.70 | PIK3C2B (0.42) | ALDH1A1KDM4ETSHRLMNAHPGD | |
| SCHEMBL30933431 | 0.70 | PIK3C2B (0.42) | ALDH1A1KDM4ETSHRLMNAHPGD | |
| SCHEMBL24770073 | 0.70 | POLQ (0.47) | ALDH1A1LMNAHAVCR2MEN1KMT2A | |
| SCHEMBL30017896 | 0.70 | POLQ (0.47) | ALDH1A1LMNAHAVCR2MEN1KMT2A | |
| SCHEMBL28630088 | 0.70 | KDM4E (0.43) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL20768125 | 0.70 | MAPT (0.41) | MAPTALDH1A1KDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |