Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269377 | 0.94 | TDP1 (0.47) | TDP1POLBNPSR1EPHX1MAOA | |
| SCHEMBL28269379 | 0.94 | TDP1 (0.47) | TDP1POLBNPSR1EPHX1MAOA | |
| SCHEMBL28629697 | 0.92 | EPHX1 (0.48) | TDP1POLBNPSR1EPHX1MAOA | |
| SCHEMBL28581494 | 0.90 | EPHX1 (0.46) | TDP1POLBNPSR1EPHX1MAOA | |
| SCHEMBL19708437 | 0.90 | EPHX1 (0.46) | TDP1POLBNPSR1EPHX1MAOA | |
| SCHEMBL28628321 | 0.89 | EPHX1 (0.48) | TDP1POLBNPSR1EPHX1MAOA | |
| SCHEMBL21009781 | 0.89 | EPHX1 (0.46) | TDP1POLBNPSR1EPHX1MAOA | |
| SCHEMBL28610942 | 0.85 | POLB (0.43) | TDP1POLBNPSR1MAOAMAOB | |
| SCHEMBL28169257 | 0.84 | POLB (0.40) | TDP1POLBNPSR1MAOAMAOB | |
| SCHEMBL28619779 | 0.83 | EPHX2 (0.49) | TDP1POLBNPSR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098871-B | Phenyl propionamide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |