SCHEMBL2861899

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2857674	0.88	MAP2K4 (0.60)	MAP2K4MAPK1MAPK6MAPKAPK3GSK3A
	SCHEMBL2864745	0.87	MAP2K4 (0.58)	MAP2K4MAPK1MAPK6MAPKAPK3GSK3A
	SCHEMBL2864251	0.83	MAP2K4 (0.54)	MAP2K4MAPK1MAPK6MAPKAPK3GSK3A
	SCHEMBL2866807	0.82	DYRK1A (0.52)	MAP2K4GSK3AGSK3BMAP2K7
	SCHEMBL2860783	0.81	MAP2K4 (0.52)	MAP2K4MAPK1MAPK6MAPKAPK3GSK3A
	SCHEMBL4334601	0.80	MAP4K4 (0.50)	MAP2K4MAPK1GSK3AGSK3BMAP2K7
	SCHEMBL2859867	0.79	MAP2K4 (0.81)	MAP2K4MAPK1MAPK6MAPKAPK3GSK3A
	SCHEMBL2858476	0.79	MAP2K4 (0.68)	MAP2K4MAPK1MAPK6MAPKAPK3CSNK2A2
	SCHEMBL4332627	0.79	MAPK8 (0.49)	MAP2K4MAPK1HSP90AA1HSP90AB1
	SCHEMBL2858316	0.77	MAP2K4 (0.52)	MAP2K4MAPK1MAPK6MAPKAPK3DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.