Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099052 | 0.81 | KMT2A (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL8350940 | 0.79 | MEN1 (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL5249245 | 0.79 | KMT2A (0.50) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL12510434 | 0.78 | MEN1 (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL1423598 | 0.78 | KDM4C (0.37) | MEN1KMT2AKDM4CL3MBTL1HRH3 | |
| SCHEMBL9335071 | 0.78 | KMT2A (0.61) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL6000386 | 0.77 | MEN1 (0.48) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL16376197 | 0.77 | MEN1 (0.56) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL1345450 | 0.77 | KDM4C (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| SCHEMBL8500626 | 0.76 | MEN1 (0.55) | MEN1KMT2AKDM4CL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214283-B | Preparation method of furan macrocyclic compound, prepared furan macrocyclic compound and application | 华南理工大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113214283-A | Preparation method of furan macrocyclic compound, prepared furan macrocyclic compound and application | 华南理工大学 | 2021-08-06 | — | — | CN | disclosed |