SCHEMBL28619641

SCHEMBL28619641

CCN(CC)Cc1cccc(C(C)=O)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
BRD4 O60885 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP1A2 P05177 1/20 0.39
ALDH1A1 P00352 2/20 0.38
IRAK4 Q9NWZ3 1/20 0.37
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
MAPK8 P45983 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
HRH3 Q9Y5N1 1/20 0.35
CCR4 P51679 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698577 0.87 KDM4E (0.52) BRD4CYP1A2KDM4ELMNAALOX15
SCHEMBL9297586 0.83 NPSR1 (0.41) BRD4NPSR1CYP1A2ALDH1A1IRAK4
SCHEMBL24922464 0.82 GRIN2D (0.35) POLBBRD4NPSR1CYP1A2ALDH1A1
SCHEMBL1698856 0.81 CYP1A2 (0.66) POLBCYP1A2ALDH1A1KDM4ETSHR
SCHEMBL12432224 0.80 IRAK4 (0.49) POLBBRD4NPSR1CYP1A2ALDH1A1
SCHEMBL522437 0.80 GRIN2D (0.44) POLBNPSR1ALDH1A1CDK5CDK5R1
SCHEMBL6898745 0.79 KCNH2 (0.46) BRD4NPSR1CYP1A2ALDH1A1IRAK4
SCHEMBL30401197 0.79 NPSR1 (0.43) BRD4NPSR1CYP1A2ALDH1A1IRAK4
SCHEMBL4859332 0.79 NPSR1 (0.43) BRD4NPSR1CYP1A2ALDH1A1IRAK4
Alcohol SCHEMBL4865562 0.77 NPSR1 (0.42) BRD4NPSR1CYP1A2ALDH1A1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111393-B NNN ligand compound, cobalt-NNN complex, preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2021-08-27 CN disclosed