Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 18/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.45 |
| ▸ | METTL3 | Q86U44 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20049165 | 0.86 | PRMT5 (0.47) | PRMT5WDR77METTL3 | |
| SCHEMBL28622179 | 0.85 | PRMT5 (0.68) | PRMT5WDR77METTL3 | |
| SCHEMBL28632386 | 0.84 | PRMT5 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL22743967 | 0.84 | PRMT5 (0.52) | PRMT5WDR77METTL3 | |
| SCHEMBL28621686 | 0.82 | PRMT5 (0.48) | PRMT5WDR77METTL3 | |
| SCHEMBL21312862 | 0.82 | PRMT5 (0.53) | PRMT5WDR77METTL3 | |
| SCHEMBL28628493 | 0.82 | PRMT5 (0.47) | PRMT5WDR77METTL3 | |
| SCHEMBL28922212 | 0.81 | PRMT5 (0.48) | PRMT5WDR77METTL3 | |
| SCHEMBL22002283 | 0.79 | PRMT5 (0.71) | PRMT5WDR77METTL3 | |
| SCHEMBL22684698 | 0.79 | PRMT5 (0.71) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234079-B | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113234079-A | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2021-08-10 | — | — | CN | disclosed |