Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28546134 | 0.74 | AKT1 (0.43) | AKT1AKT2AURKAAURKBINCENP | |
| SCHEMBL30823569 | 0.72 | AKT2 (0.59) | AKT1AKT2AURKAAURKBINCENP | |
| SCHEMBL30823568 | 0.72 | AKT2 (0.59) | AKT1AKT2AURKAAURKBINCENP | |
| SCHEMBL3740850 | 0.71 | AKT2 (0.70) | AKT1AKT2PIM1PIM3PIM2 | |
| SCHEMBL22192214 | 0.70 | LRRK2 (0.47) | AKT1AKT2AURKAAURKBINCENP | |
| SCHEMBL22192677 | 0.70 | AKT2 (0.50) | AKT1AKT2AURKAAURKBINCENP | |
| SCHEMBL22192203 | 0.70 | FEN1 (0.50) | AKT1AKT2AURKAAURKBINCENP | |
| SCHEMBL29533228 | 0.69 | AKT2 (0.61) | AKT1AKT2PIM1PIM3PIM2 | |
| SCHEMBL16432987 | 0.69 | AKT2 (0.76) | AKT1AKT2PIM1PIM3PIM2 | |
| SCHEMBL15689115 | 0.69 | AKT2 (0.76) | AKT1AKT2PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112625069-B | Cobalt metal organic framework material based on pyrene tetrapyrazole ligand, preparation method and application thereof | 北京工业大学 | 2022-05-17 | — | — | CN | claimed |
| CN-119331264-A | Pyrenyl metal organic framework material suitable for low-temperature methane adsorption storage, and preparation and application thereof | 浙江大学杭州国际科创中心 | 2025-01-21 | — | — | CN | disclosed |
| CN-112625069-B | Cobalt metal organic framework material based on pyrene tetrapyrazole ligand, preparation method and application thereof | 北京工业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-112625069-B | Cobalt metal organic framework material based on pyrene tetrapyrazole ligand, preparation method and application thereof | 北京工业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113201142-A | Hydrogen bond organic grid material based on aromatic tetrapyrazole and preparation method and application thereof | 北京工业大学 | 2021-08-03 | — | — | CN | disclosed |