Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856491 | 0.88 | TSHR (0.56) | PRNPRXFP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13155421 | 0.88 | MAPT (0.50) | PRNPRXFP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28719424 | 0.86 | TSHR (0.47) | PRNPTSHRMCL1ALDH1A1HPGD | |
| SCHEMBL29433694 | 0.86 | TSHR (0.47) | PRNPTSHRMCL1ALDH1A1HPGD | |
| SCHEMBL10913333 | 0.83 | MCL1 (0.48) | MCL1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL22620634 | 0.83 | PLK1 (0.56) | PRNPRXFP1HIF1ANPSR1TSHR | |
| SCHEMBL31424312 | 0.81 | KCNH2 (0.46) | PRNPTSHRMCL1ALDH1A1HPGD | |
| SCHEMBL16684635 | 0.80 | MCL1 (0.67) | PRNPTSHRMCL1ALDH1A1HPGD | |
| SCHEMBL566348 | 0.79 | KDM4E (0.68) | CYP2C9ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL2773751 | 0.78 | MCL1 (0.58) | NPSR1TSHRMCL1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302185-A | Benzofuran-6-carboxamide derivatives, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |