Pyrazine

Pyrazine

SCHEMBL28622202

N#Cc1ccccc1C#N.c1cnccn1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
HTT P42858 2/20 0.47
CYP19A1 P11511 2/20 0.46
NCOA3 Q9Y6Q9 1/20 0.42
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ESR2 Q92731 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28719261 0.90 TSHR (0.46) TSHRHTTCYP19A1NCOA3CA1
Hydrochloric Acid SCHEMBL28964120 0.85 TSHR (0.57) TSHRHTTCYP19A1CA1CA2
Water SCHEMBL19410621 0.85 TSHR (0.63) TSHRHTTCA1CA2ESR2
SCHEMBL29352197 0.85 TSHR (0.63) TSHRHTTCA1CA2ESR2
SCHEMBL2818597 0.85 TSHR (0.63) TSHRHTTCA1CA2ESR2
Water SCHEMBL27896186 0.85 TSHR (0.63) TSHRHTTCA1CA2ESR2
SCHEMBL57480 0.85 TSHR (0.63) TSHRHTTCA1CA2ESR2
Dalfampridine SCHEMBL18491229 0.84 TSHR (0.56) TSHRHTTCYP19A1NCOA3ALDH1A1
SCHEMBL3959857 0.82 TSHR (0.60) TSHRHTTCA1CA2ESR2
Hydrogen Sulfide SCHEMBL1324202 0.82 TSHR (0.60) TSHRHTTCA1CA2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167927-B dicyano-N-heterocyclic compound, light-emitting material, and light-emitting element using same 国立大学法人九州大学 2021-09-24 CN disclosed