Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542219 | 0.81 | HPGD (0.49) | MAPTLMNAHPGDL3MBTL1TDP1 | |
| SCHEMBL11422270 | 0.79 | MAPT (0.47) | MAPTLMNAPOLBL3MBTL1TDP1 | |
| SCHEMBL28043023 | 0.79 | TDP1 (0.39) | MAPTLMNAPOLBHPGDL3MBTL1 | |
| SCHEMBL8005808 | 0.79 | MAPT (0.40) | MAPTHPGDL3MBTL1KMT2ATSHR | |
| SCHEMBL8171785 | 0.79 | TSHR (0.53) | MAPTLMNAHPGDL3MBTL1TDP1 | |
| SCHEMBL1697056 | 0.78 | MAPT (0.57) | MAPTLMNAPOLBHPGDL3MBTL1 | |
| SCHEMBL5547389 | 0.78 | HSD17B3 (0.51) | MAPTLMNAL3MBTL1TDP1KMT2A | |
| SCHEMBL1416098 | 0.78 | HPGD (0.59) | HPGDKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL687760 | 0.77 | MAPT (0.46) | MAPTLMNAHPGDL3MBTL1TDP1 | |
| SCHEMBL5548382 | 0.77 | HSD17B3 (0.53) | MAPTLMNAL3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135922-A | Azacycloheptane [4,3,2-cd ] isoindol-2-one derivatives and application thereof | 中国药科大学 | 2021-07-20 | — | — | CN | claimed |
| CN-113135922-A | Azacycloheptane [4,3,2-cd ] isoindol-2-one derivatives and application thereof | 中国药科大学 | 2021-07-20 | — | — | CN | disclosed |