Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 2/20 | 0.35 |
| ▸ | EEF2 | P13639 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706474 | 0.98 | KMT2A (0.40) | KMT2AALDH1A1POLBTYREEF2K | |
| Hydrochloric Acid SCHEMBL28978565 | 0.96 | KMT2A (0.43) | KMT2AALDH1A1POLBTYREEF2K | |
| SCHEMBL17706456 | 0.91 | MEN1 (0.41) | KMT2AEEF2KEEF2MEN1PLK4 | |
| SCHEMBL486387 | 0.86 | TYR (0.35) | TYR | |
| SCHEMBL486627 | 0.77 | — | — | |
| Iodide SCHEMBL596677 | 0.69 | EEF2K (0.48) | KMT2AALDH1A1POLBTYREEF2K | |
| Phosphoric Acid SCHEMBL28472026 | 0.68 | — | — | |
| SCHEMBL28385710 | 0.67 | KMT2A (0.46) | KMT2AALDH1A1POLBTYREEF2K | |
| SCHEMBL294425 | 0.67 | KMT2A (0.46) | KMT2AALDH1A1POLBTYREEF2K | |
| Bromide SCHEMBL711969 | 0.65 | CA1 (0.49) | KMT2AALDH1A1POLBTYREEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109887754-B | Monoatomic Pt counter electrode and preparation method and application thereof | 东莞理工学院 | 2021-08-20 | — | — | CN | disclosed |