Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA6 | P23280 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28625400 | 1.00 | PAOX (0.40) | PAOXALDH1A1CA12CA6CA7 | |
| Acetic Acid SCHEMBL896272 | 0.98 | PAOX (0.41) | PAOXALDH1A1CA12CA6CA7 | |
| Acetic Acid SCHEMBL22342077 | 0.98 | PAOX (0.41) | PAOXALDH1A1CA12CA6CA7 | |
| Acetic Acid SCHEMBL4394144 | 0.98 | PAOX (0.41) | PAOXALDH1A1CA12CA6CA7 | |
| Acetic Acid SCHEMBL2347228 | 0.97 | PAOX (0.40) | PAOXALDH1A1CA12CA6CA7 | |
| Acetic Acid SCHEMBL485881 | 0.97 | PAOX (0.40) | PAOXALDH1A1CA12CA6CA7 | |
| Acetone SCHEMBL28527393 | 0.93 | PAOX (0.42) | PAOXALDH1A1CA12CA6CA7 | |
| Acetic Acid SCHEMBL4300678 | 0.90 | PAOX (0.40) | PAOXALDH1A1CA12CA6CA7 | |
| Ammonia Solution, Strong SCHEMBL10482257 | 0.89 | CA12 (0.46) | ALDH1A1CA12CA6CA7CA9 | |
| Ammonia Solution, Strong SCHEMBL21530853 | 0.89 | CA12 (0.46) | ALDH1A1CA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112607841-A | Efficient sewage treatment additive and preparation method thereof | 纪德军 | 2021-04-06 | — | — | CN | claimed |
| CN-111925170-A | Environment-friendly pervious concrete and preparation method thereof | 韩昌龙 | 2020-11-13 | — | — | CN | claimed |
| CN-112607841-A | Efficient sewage treatment additive and preparation method thereof | 纪德军 | 2021-04-06 | — | — | CN | disclosed |
| CN-112607841-A | Efficient sewage treatment additive and preparation method thereof | 纪德军 | 2021-04-06 | — | — | CN | disclosed |
| CN-111925170-A | Environment-friendly pervious concrete and preparation method thereof | 韩昌龙 | 2020-11-13 | — | — | CN | disclosed |
| CN-111925170-A | Environment-friendly pervious concrete and preparation method thereof | 韩昌龙 | 2020-11-13 | — | — | CN | disclosed |