Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244433 | 0.86 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL17187306 | 0.82 | HCAR2 (0.68) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL2114928 | 0.79 | HCAR2 (0.47) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL244432 | 0.79 | HCAR2 (0.47) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL28613247 | 0.79 | HCAR2 (0.74) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL10769985 | 0.78 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL10036927 | 0.78 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL599553 | 0.78 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL28025601 | 0.78 | TSHR (0.55) | HCAR2ATMALDH1A1NPSR1HSD17B10 | |
| SCHEMBL27722644 | 0.77 | HCAR2 (0.53) | HCAR2ATMMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115531366-A | Method of treating multiple sclerosis | 渤健马萨诸塞州股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115501218-A | Methods of treating multiple sclerosis | 渤健马萨诸塞州股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-113368092-A | Methods of treating multiple sclerosis | 比奥根玛公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-113368093-A | Methods of treating multiple sclerosis | 比奥根玛公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-113368091-A | Methods of treating multiple sclerosis | 比奥根玛公司 | 2021-09-10 | — | — | CN | disclosed |