Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | PLD2 | O14939 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30175940 | 0.93 | KDM4E (0.87) | KDM4EHSD17B10ALDH1A1MAPTCYP1A2 | |
| SCHEMBL14006089 | 0.92 | KDM4E (0.85) | KDM4EHSD17B10ALDH1A1MAPTSLC6A2 | |
| SCHEMBL27015521 | 0.87 | KDM4E (0.77) | KDM4EHSD17B10ALDH1A1MAPTPLD2 | |
| SCHEMBL2760134 | 0.85 | KDM4E (0.74) | KDM4EHSD17B10ALDH1A1MAPTPLD2 | |
| SCHEMBL7894771 | 0.85 | KDM4E (0.74) | KDM4EHSD17B10ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7947246 | 0.85 | KDM4E (0.74) | KDM4EHSD17B10ALDH1A1MAPTCYP1A2 | |
| SCHEMBL24076565 | 0.84 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1PLD2SLC6A2 | |
| Hydrochloric Acid SCHEMBL7884855 | 0.83 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1MAPTPLD2 | |
| Hydrochloric Acid SCHEMBL8629286 | 0.83 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1MAPTPLD2 | |
| SCHEMBL25040938 | 0.82 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530335-B | Indole compound and preparation method and application thereof | 华南农业大学 | 2021-08-31 | — | — | CN | disclosed |