SCHEMBL28624844

SCHEMBL28624844

COc1ccccc1COc1ccc(Br)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
IDO1 P14902 2/20 0.53
ABCB1 P08183 2/20 0.51
PARP14 Q460N5 1/20 0.50
PARP10 Q53GL7 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
ATM Q13315 2/20 0.49
BCHE P06276 1/20 0.48
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
MAPT P10636 2/20 0.46
HTR1A P08908 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4779293 0.85 ABCB1 (0.62) ALDH1A1MEN1KMT2AIDO1ABCB1
SCHEMBL5710347 0.85 MAPT (0.51) IDO1L3MBTL1ATMMAPTHPGD
SCHEMBL29036345 0.84 IDO1 (0.55) ALDH1A1MEN1KMT2ACYP1A2CYP2C19
SCHEMBL15033480 0.84 NPC1 (0.57) MEN1KMT2AIDO1ABCB1PARP14
SCHEMBL15033567 0.83 IDO1 (0.58) ALDH1A1IDO1ABCB1PARP14PARP10
SCHEMBL14163906 0.81 ABCB1 (0.54) MEN1KMT2AIDO1ABCB1PARP14
SCHEMBL2494662 0.81 MAPT (0.50) ALDH1A1ABCB1L3MBTL1ATMBCHE
SCHEMBL20085462 0.80 IDO1 (0.50) CYP3A4CYP2D6IDO1ABCB1PARP14
SCHEMBL13450812 0.80 IDO1 (0.50) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL21340422 0.80 IDO1 (0.50) ALDH1A1IDO1ABCB1PARP14PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107699252-B Polymeric liquid crystal compound and preparation method and application thereof 北京八亿时空液晶科技股份有限公司 2021-09-07 CN disclosed