Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 12/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.50 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953559 | 0.89 | CDC7 (0.48) | SREBF2CDC7DBF4SREBF1MAPT | |
| SCHEMBL27943071 | 0.80 | CDC7 (0.46) | SREBF2CDC7DBF4SREBF1MAPT | |
| SCHEMBL27953527 | 0.80 | CDC7 (0.43) | SREBF2CDC7DBF4SREBF1MAPT | |
| SCHEMBL27942959 | 0.79 | CDC7 (0.44) | SREBF2CDC7DBF4SREBF1MAPT | |
| SCHEMBL27858910 | 0.78 | CDC7 (0.46) | SREBF2CDC7DBF4SREBF1MAPT | |
| SCHEMBL27942962 | 0.78 | CDC7 (0.46) | SREBF2CDC7DBF4SREBF1 | |
| SCHEMBL27942928 | 0.78 | FFAR1 (0.49) | SREBF2CDC7DBF4SREBF1MAPT | |
| SCHEMBL27942915 | 0.78 | FFAR1 (0.55) | SREBF2CDC7DBF4SREBF1MAPT | |
| Bromobenzene SCHEMBL27953553 | 0.78 | CDC7 (0.46) | SREBF2CDC7DBF4SREBF1MAPT | |
| SCHEMBL14840661 | 0.77 | CDC7 (0.62) | SREBF2CDC7DBF4SREBF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149980-A | Tert-butyloxycarbonyl micromolecule organic compound targeting PUF60, derivative thereof and application thereof | 上海市奉贤区中心医院 | 2021-07-23 | — | — | CN | disclosed |