Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PRCP | P42785 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642107 | 1.00 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL28626823 | 1.00 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL5898621 | 1.00 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL28627160 | 1.00 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL28622823 | 1.00 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL28631573 | 1.00 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL5898624 | 0.96 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL5898611 | 0.95 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL28629956 | 0.95 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 | |
| SCHEMBL6242176 | 0.95 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2PRCPHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |