Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.66 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622615 | 0.84 | CXCR1 (0.64) | CXCR1CXCR2ALDH1A1 | |
| SCHEMBL6802546 | 0.83 | CXCR1 (0.63) | CXCR1CXCR2KMT2ALMNAGPR88 | |
| SCHEMBL11773513 | 0.80 | CXCR1 (0.44) | CXCR1CXCR2ALOX5TDP1KMT2A | |
| SCHEMBL13952025 | 0.80 | CXCR1 (1.00) | CXCR1CXCR2ALOX5LMNACHRM1 | |
| SCHEMBL13712793 | 0.79 | CHRM1 (0.62) | CXCR1CXCR2ALOX5KMT2ALMNA | |
| SCHEMBL12424105 | 0.79 | HPGD (0.51) | ALOX5TDP1KMT2AACHE | |
| SCHEMBL30641550 | 0.77 | HPGD (0.50) | ALOX5TDP1KMT2AACHE | |
| SCHEMBL14135290 | 0.76 | MAPT (0.65) | TDP1KMT2ALMNAMAPTHTT | |
| SCHEMBL9692381 | 0.76 | TDP1 (0.44) | CXCR1CXCR2ALOX5TDP1KMT2A | |
| SCHEMBL16750533 | 0.74 | EPHX1 (0.60) | ALOX5KMT2ALMNAACHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214134-B | Synthesis method of quaternary carbon oxoindole skeleton | 南通大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113214134-A | Synthesis method of quaternary carbon oxoindole skeleton | 南通大学 | 2021-08-06 | — | — | CN | disclosed |