Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21965737 | 0.83 | DDB1 (0.67) | DDB1CRBN | |
| SCHEMBL21965795 | 0.81 | DDB1 (0.70) | DDB1CRBN | |
| SCHEMBL22117787 | 0.79 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL22117653 | 0.79 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL22117604 | 0.79 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL21966106 | 0.79 | CRBN (0.62) | DDB1CRBN | |
| SCHEMBL30401772 | 0.79 | CRBN (0.74) | DDB1CRBN | |
| Bromide SCHEMBL22128737 | 0.78 | CRBN (0.97) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL22117857 | 0.78 | CRBN (0.97) | DDB1CRBN | |
| SCHEMBL30936762 | 0.78 | DDB1 (0.72) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219606-A | Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same | 细胞基因公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113453681-B | Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same | 细胞基因公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116507333-A | Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116157390-A | Compounds for androgen receptor degradation and pharmaceutical uses thereof | 尤比克斯治疗公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115835866-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-113453681-A | Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same | 细胞基因公司 | 2021-09-28 | — | — | CN | disclosed |