Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597704 | 0.83 | MAPK14 (0.46) | MAPK14GSK3BDYRK1ANPC1RAB9A | |
| SCHEMBL28620607 | 0.82 | MAPK14 (0.44) | MAPK14GSK3BDYRK1ANPC1IDH1 | |
| SCHEMBL28617347 | 0.80 | MAPK14 (0.42) | MAPK14GSK3BDYRK1ANPC1RAB9A | |
| SCHEMBL21597716 | 0.80 | MAPK14 (0.46) | MAPK14GSK3BDYRK1ACYP17A1BRD9 | |
| SCHEMBL27415470 | 0.79 | MAPK14 (0.44) | MAPK14GSK3BDYRK1ANPC1RAB9A | |
| SCHEMBL21604145 | 0.78 | MAPK14 (0.46) | MAPK14GSK3BDYRK1ACYP17A1SMN1; SMN2 | |
| SCHEMBL21604120 | 0.77 | CACNB4 (0.43) | MAPK14GSK3BDYRK1ACYP17A1BRD9 | |
| SCHEMBL6845100 | 0.77 | MAPK14 (0.48) | MAPK14GSK3BDYRK1ASMN1; SMN2MAPT | |
| SCHEMBL35210874 | 0.77 | SMN1; SMN2 (0.57) | MAPK14GSK3BDYRK1ASMN1; SMN2BRD9 | |
| SCHEMBL2175532 | 0.76 | MAPK14 (0.47) | MAPK14GSK3BDYRK1ACYP17A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |