SCHEMBL28627401

SCHEMBL28627401

Cc1c(C(=O)C(=O)NC2(c3c[nH]nn3)CC(F)C2F)c2n(c1C(=O)Nc1ccc(F)c(C#N)c1)CCC2

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20259592 0.88 SLC10A1 (0.69) SLC10A1
SCHEMBL19920680 0.86 SLC10A1 (0.79) SLC10A1
SCHEMBL20252977 0.81 SLC10A1 (0.61) SLC10A1
SCHEMBL21378241 0.81 SLC10A1 (0.71) SLC10A1
SCHEMBL20252892 0.80 SLC10A1 (0.70) SLC10A1
SCHEMBL19900866 0.79 SLC10A1 (0.77) SLC10A1
SCHEMBL23766525 0.78 SLC10A1 (0.68) SLC10A1
SCHEMBL19900731 0.77 SLC10A1 (0.78) SLC10A1
SCHEMBL19900779 0.77 SLC10A1 (0.78) SLC10A1
SCHEMBL20252899 0.77 SLC10A1 (0.69) SLC10A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113620960-A Substituted pyrrolizine compounds and uses thereof 吉利德科学公司 2021-11-09 CN disclosed
CN-109790168-B Substituted pyrrolizine compounds and uses thereof 吉利德科学公司 2021-09-17 CN disclosed