SCHEMBL28628101

SCHEMBL28628101

N=C(N)c1cncc(C(=N)N)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 6/20 0.44
PRSS3 P35030 5/20 0.44
PRSS2 P07478 4/20 0.44
C1S P09871 3/20 0.44
F2 P00734 5/20 0.42
F10 P00742 1/20 0.42
F12 P00748 1/20 0.42
F7 P08709 1/20 0.42
F3 P13726 1/20 0.42
PKM P14618 1/20 0.42
PLAU P00749 3/20 0.40
LMNA P02545 2/20 0.40
BLM P54132 1/20 0.40
MASP2 O00187 1/20 0.40
THPO P40225 1/20 0.40
KMT2A Q03164 2/20 0.39
RECQL P46063 1/20 0.39
APEX1 P27695 1/20 0.39
ALDH1A1 P00352 2/20 0.38
PLG P00747 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14625013 0.84 PRSS1 (0.37) PRSS1PRSS3PRSS2C1SF2
SCHEMBL30936046 0.84 HCAR2 (0.55) PRSS1PRSS3PRSS2C1SF2
SCHEMBL6652760 0.84 POLB (0.55) C1SKMT2AALDH1A1KDM4EMEN1
SCHEMBL17751167 0.84 PRSS1 (0.58) PRSS1PRSS3PRSS2C1SF2
SCHEMBL8005179 0.84 HCAR2 (0.55) PRSS1PRSS3PRSS2C1SF2
Hydrochloric Acid SCHEMBL20839163 0.82 HCAR2 (0.53) PRSS1PRSS3PRSS2C1SF2
Hydrochloric Acid SCHEMBL26107499 0.82 POLB (0.53) C1SKMT2AALDH1A1KDM4EMEN1
Hydrochloric Acid SCHEMBL5916519 0.82 PRSS1 (0.56) PRSS1PRSS3PRSS2C1SF2
Hydrochloric Acid SCHEMBL14486940 0.82 HCAR2 (0.53) PRSS1PRSS3PRSS2C1SF2
SCHEMBL1924159 0.79 SMYD3 (0.46) PRSS1PRSS3PRSS2C1SF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836101-A Perovskite solar cell based on diamine molten salt surface modification and preparation method thereof 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN claimed
CN-109111376-B 2, 5-dideoxy streptomycin derivative and application thereof 四川医立特生物医药有限公司 2021-09-14 CN disclosed