SCHEMBL28628169

SCHEMBL28628169

N#Cc1cc2cc(Br)ccc2cc1I

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.42
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CHEK1 O14757 1/20 0.37
MAOB P27338 3/20 0.36
MAOA P21397 2/20 0.36
GPR35 Q9HC97 2/20 0.36
NSD2 O96028 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
CASP1 P29466 1/20 0.35
HTT P42858 1/20 0.35
CASP7 P55210 1/20 0.35
CASP6 P55212 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28628069 1.00 CYP2A6 (0.42) CYP2A6KDM4EMAPTMEN1KMT2A
SCHEMBL29597014 0.86 CYP2A6 (0.50) CYP2A6KDM4EMAPTMEN1KMT2A
SCHEMBL7590901 0.86 CYP2A6 (0.50) CYP2A6KDM4EMAPTMEN1KMT2A
SCHEMBL28646812 0.78 CA1 (0.53) CYP2A6KDM4EMAPTMEN1KMT2A
SCHEMBL142523 0.78 MAOB (0.41) CHEK1MAOBMAOALMNABACE1
SCHEMBL16534885 0.78 MAOB (0.50) CYP2A6CHEK1MAOBMAOALMNA
SCHEMBL29439578 0.78 MAOB (0.41) CHEK1MAOBMAOALMNABACE1
SCHEMBL8404526 0.78 CYP2A6 (0.42) CYP2A6KDM4EMAPTMEN1KMT2A
SCHEMBL26623457 0.78 CYP2A6 (0.42) CYP2A6KDM4EMAPTMEN1KMT2A
SCHEMBL22155637 0.72 MAOB (0.44) KDM4EMAPTALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429348-B Anthracene imidazole derivative, organic electroluminescent material and consumer product 北京八亿时空液晶科技股份有限公司 2021-12-14 CN disclosed
CN-113429348-A Anthracene imidazole derivative, organic electroluminescent material and consumer product 北京八亿时空液晶科技股份有限公司 2021-09-24 CN disclosed